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KMID : 0860920180200010072
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2018 Volume.20 No. 1 p.72 ~ p.76
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A Case of Peripheral Polyneuropathy Presenting with Central Retinal Artery Occlusion, Rapid Progressive Glomerulonephritis due to ANCA Associated Vasculitis
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Park Seung-Wan
Ryu Byong-Ju
Moon Jeong-Bo
Kwak Ho-Jun
Kim Yun-Hee
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Abstract
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We report a case of asymmetric polyneuropathy with left central retinal artery occlusion, rapid progressive glomerulonephritis (RPGN) due to Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). A-64-year-old man started to have numbness and weakness in both legs. One month later, he suddenly lost a vision in his left eye and had swelling in both legs. Thereafter, weakness progressed to both upper extremities. Multiple eye retinal hemorrhages and cherry-red spots were observed on fundus examination and were diagnosed as central retinal artery occlusion. Pauci-immune crescentic glomerulonephritis were identified after renal biopsy. Nerve conduction study was performed and the patient was diagnosed by peripheral polyneuropathy involving both upper and lower extremities. Clinically, we diagnosed a vasculitis, especially microscopic polyangiitis (MPA).
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KEYWORD
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antineutrophil cytoplasmic antibody, central retinal artery occlusion, polyneuropathy
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